Abstracto

An efficient synthesis of thiocoumarin catalysed by triethylamine under solvent free conditions

Nepram Sushuma Devi, Sarangthem Joychandra Singh, Okram Mukherjee Singh

An efficient synthesis of thiocoumarin has been developed by the reaction of easily accessible â-oxodithioesters and salicylaldehyde derivatives in the presence of mild, nonnucleophilic base, triethylamine under solvent free conditions. The mild reaction conditions, high yields, operational simplicity and shorter reaction period illustrate the good synthetic utility of this method.