Abstracto

Antimicrobial and antioxidant potent substituted styryl â-hydroxy-á-naphthyl ketones

Ganesamoorthy Thirunarayanan, Ganesan Vanangamudi, Muthuvel Subramanian

A series of twelve â-hydroxy-á-naphthyl chalcones [2E-1-(2-hydroxy-1- naphthyl)-3-(substituted phenyl)-2-propen-1-ones] were synthesized by Crossed-Aldol condensation of 1-acetyl-2-hydroxy naphthalene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants and spectral data. The antimicrobial and antioxidant activities of these â-hydroxy-á-naphthyl 2-propen-1-ones have been studied using Bauer-Kirby and DPPH radical scavenging methods respectively.