Abstracto

Effect of wet cupping on antioxidant status in peripheral and cupping blood of non-athletes and athletes

Masoud Mashhadi Akbar Boojar, Nazmodin Noory, Manoochehr Mashhadi Akbar Boojar

Objective: ROS are highly reactive molecules that reactwith cellular components, resulting in oxidative damage. They are involved in many degenerative conditions. In other side, wet cupping is an effective method of treating radical-related disorders. This study is aimed to evaluate the effect of wet cupping together with sporting on antioxidant defense system. Subjects and Methods: In this study 40 healthy, non-smoker men were assigned into non-, amateur, and professional athlete groups. They were subjected to two samplings with one week interval. The levels of antioxidant enzyme activities, oxidative damage biomarkers, and vitamins C and E were evaluated in blood samples. Results: We observed increased antioxidant enzyme activities with sporting activity in both peripheral and cupping blood. Low enzyme activities and high level of oxidative damage biomarkers were observed in cupping blood with respect to peripheral blood samples. In addition, the level of enzyme activities elevated considerably in second sampling with respect to first sampling in both peripheral and cupping blood. The level of oxidative damage biomarkers in second sampling was significantly lower than first sampling. In both kind of blood, we did not observe any significant difference in vitamin C and E at first and/or second sampling. Conclusions: Sporting activity together with wet cupping induced adaptive responses in antioxidant and repair systems, increased protection of cells against ROS and decreased the accumulation of oxidative damage biomarkers.