Abstracto

New flavanones from the seeds of Rumex vesicarius L.

Wadood A.Siddiqui, Mohd. Ali, Kamran J.Naquvi, Shahnaz S.Husain

Rumex vesicarius L. (Polygonaceae) is an annual, monoecious glabrous, pale green herb cultivated as a leafy vegetable in many parts of India. The seeds are utilized as a refrigerant, to cure dysentery and as an antidote for scorpion venom. The seed powder is taken orally to treat liver diseases and as a laxative. Phytochemical investigation of themethanolic extract of seeds of R. vesicarius resulted in the isolation of two new flavanones characterized as 5,7,3'-trihydroxy-4'-methoxy-8-(3''-methyl-5''-methylene)hexenyl flavanone (vesicariaflavanoneA, 4) and 5,7,3',4'-tetrahydroxy-6-methoxy-8- (3''-methylene)-hexenylflavanone (vesicariaflavoneB, 5) alongwith the fatty acid glycerides identified as glyceryl-1-octadec-9'-enoate-3-phosphate (1), glyceryl-1,2-bis-hexadecanoate-3-phosphate (2) and glyceryl-1-octadec-9'- enoate-2-octahexanoate-3-phosphate (3). The structures of all the isolated phytoconstituents have been estabilished on the basis of spectral data analysis and chemical reactions.