Ciencias ambientales: una revista india
ISSN (PRINT):0974-7451

Abstracto

Synthesis of pranlukast

Yue Zhang, Hai-wen Song, Yi-feng Yu, Ting-ting liu, Shi-xia Xu, Man Du, Yongguo Wang


4-(4-Phenylbutoxy)benzoic acid (2), which was prepared from tetrahydrofuran (4) by ring-opening, Friedel-Crafts alkylation, bromination and etherification, reacted with 3-amino-2-hydroxyacetophenone (3) to give 3-[4-(4-phenylbutoxy)benzoic amide]-2- hydroxyacetophenone (11), followed by reacting in the presence of 1H-tetrazol-5-ethyl formate (12) and cyclization to give pranlukast (1)with the overall yield of 24.7%(based on 4).


Indexado en

  • CAS
  • Google Académico
  • Abrir puerta J
  • Infraestructura Nacional del Conocimiento de China (CNKI)
  • CiteFactor
  • Cosmos SI
  • Directorio de indexación de revistas de investigación (DRJI)
  • Laboratorios secretos de motores de búsqueda
  • Factor de impacto del artículo académico (SAJI))
  • ICMJE

Ver más

Revista ISSN

Índice h de la revista

Flyer

Revistas de acceso abierto