Abstracto

Effect of bael bark extracts againstEscherichia coli -Afood borne pathogen

K.Prasanna, D.Raghunathan

Food borne illness has developed serious threat to children and elderly people and the causative organism is gaining resistance over usage of synthetic formulations and drugs. The usage of medicinal plants could cover up the health aspects and offer newer source of antibacterial, antifungal agents which can be effective against pathogenic organism. The increase in resistant of pathogenic food borne illness causing organism has to be declined by developing newer type of drug which is consists of significant effect over it. The Aegle marmelos [bael] of family Rutaceae is considered as sacred tree among Indians and possess good medicinal properties. The food borne pathogen Escherichia coli were tested against bark extracts of Aegle marmelos by standard well diffusion method at varying concentration from50mg/ml-250mg/ml. The extractswere prepared by standard procedure of 1:5 ratio of bark and solvent in soxhlet apparatus. The test resultswere compared with commercial antibiotic ampicillin. The sensitive of E.coli against hexane extract of bael bark is 30mm at concentration of 250mg/ml and 24mmof inhibition zone for aqueous extract of bael bark. The commercial antibiotic sensitive against test species is recorded about to be 30mmat 250mg/ml concentration. The bark extracts against E.coli were showing sensitive inhibition zones as that of the commercial antibiotic which is ofmaximumat 250mg/ml concentration and it could easily lead to the development of newer synthetic, chemical and pharmaceutical compound for the treatment or control of food borne illness which is making serious impact on both developing and developed countries. Effective studies against the definite active biological compound could be significantly studied to develop further more chemical compounds for treating other pathogens.